Thursday, April 3, 1997

 9:00           Welcoming Remarks - Dr. Fred Roberts, Director DIMACS

 9:15           Introduction and General Overview 
                Wilma Olson, Rutgers University


		Craig Benham, Mount Sinai School of Medicine (session chair)
		Biology and Physics of DNA Deformation

 9:25 	        Andrzej Stasiak, Universite de Lausanne
		Biological Function of RecA-induced DNA 
		Stretching and Unwinding 

10:05 	        Steven M. Block, Princeton University
		Stretching DNA with Optical Tweezers

10:45 - 11:15   Coffee Break

11:15 		Phil Nelson, University of Pennsylvania
		Direct Determination of DNA Twist-Stretch Coupling

11:55 		Suse Broyde,New York University 
		Computed Structures of DNA Damaged by Activated 
		Benzo[a]pyrenes

12:30           Discussion

12:40 -  2:00   Lunch Break

		Tamar Schlick, Howard Hughes Medical Institute and 
	        New York University (session chair)
		Recent Developments of Elastic Rod Models of DNA 

 2:00 		Alexander V. Vologodskii,  New York University
		Catenation Probability in Supercoiled DNA 

 2:40 		Irwin Tobias, Rutgers University
		Thermal Fluctuations in DNA Minicircles

 3:20 		Isaac Klapper, Montana State University
		Dynamics of Elastic Rods, Knots, Curves 

 4:00 -   4:30  Coffee Break
 
 4:30 		Bernard D. Coleman, Rutgers University
		Theory of the Influence of End Conditions on the 
		Tertiary Structure of DNA 

 5:10 		Marcia O. Fenley, Continuum Dynamics, Inc.
		Supercoiled DNA Polyelectrolyte

 5:50           Discussion

 6:30 -  9:00 	Dinner Reception and Poster Session



Friday, April 4, 1997 

 		Bill Bauer, State University of New York
	        Stony Brook  (session chair)
		DNA Sequence, Structure, and Activity 

 9:00 		Craig J. Benham, Mount Sinai School of Medicine
		Superhelical Duplex Destabilization and DNA Regulation 

 9:40 		Victor B. Zhurkin, National Institutes of Health
		DNA Bending and Writhing in Complexes with Proteins: 
		Analyzing Crystal Structures and Modeling the p53-DNA Complex

10:20 		Gadi Fibich, University of California, Los Angeles 
		A Mathematical Model of Transcription Regulation of a Single Gene

11:00 - 11:20   Coffee Break

		Alex Vologodskii, New York University (session chair)
		Topological Forms 

11:20 		Valentin Rybenkov and Nicholas R. Cozzarelli
	        University of California, Berkeley
		Topological Equilibrium in Circular DNA 

12:00 		Jonathan Simon, University of Iowa
		Energy, Thickness, and Compaction of Knots 

12:50           Discussion

12:50 -  1:40   Lunch Break

		Wilma Olson, Rutgers University (session chair)
		Nucleosomal DNA 

 1:40 		Ariel Prunell, Centre National de la Recherche
		Scientifique et Universite Paris
		Conformational Flexibility of the Histone (H3-H4)2 
		Tetramer of the Nucleosome Viewed Through DNA Topology 

 2:20 		David Clark, National Institutes of Health
		The Nucleosome: A Barrier to Transcription 

 3:00 		Jordanka Zlatanova, Oregon State University 
		Chromatin Higher-order Structure 

 3:40           Discussion and Refreshments

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